Signal Transduction Reagents and Kits
Aat Bioquest Calbryte 520 AM (10x50 ug)
The intracellular calcium flux assay is a widely used method in monitoring signal transduction pathways and high throughput screening of G proteinquotcoupled receptors GPCRs and calcium channel targets. This catalog is for 10x50 ug.
Selleck Chemical LLC SB202190 (FHPI) 100mg 152121-30-7
SB202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38?/? with IC50 of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1. SB202190 significantly suppresses Erastin?dependent ferroptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences AMPIPROBE Ureaplasma spp. / M. genitalium / M. hominis Assay Kit (100tests)
The AMPIPROBE Ureaplasma spp. / M. genitalium / M. hominis (UMM) Assay is a real-time polymerase chain reaction (qPCR) assay for the qualitative detection of Ureaplasma spp. (Ureaplasma parvum and Ureaplasma urealyticum), Mycoplasma genitalium, and Mycoplasma hominis DNA. The kit uses the AMPIPROBE assay platform which takes advantage of paired fluorophore- and quencher-labeled primers specific for each of the target species as well as an internal control. The kit contains all reagents necessary for PCR-based detection of Ureaplasma spp., Mycoplasma genitalium, and Mycoplasma hominis DNA. A positive PCR control consisting of a mixture of the target templates and a negative PCR control that results negative for UMM, but positive for the internal control (human β-globin). Please read the complete kit insert before performing this assay. Applications: qPCR. Species reactivity: Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma spp.
Cell Biolabs Inc ViraDuctin™ Lentivirus Transduction Kit, 40 transductions
The rate at which lentiviral vectors bind to and infect cells is mostly controlled by diffusion. During lentivirus infection, only a small fraction of the lentiviral vectors can transduce target cells. Virion adsorption is the limiting step of this process. The use of polycations, such as Polybrene, is standard in many lentiviral infection protocols owing to the observations of improved infection efficiency. Its mechanism of action is thought to involve neutralization of electrostatic repulsion between virion and cell membranes, enhancing attachment. ViraDuctin™ Lentivirus Transduction Kit is a proprietary formulation for the transduction of lentivirus. After forming a complex with lentivirus in culture medium, the ViraDuctin™ reagents typically provide higher transduction efficiency in many cell types compared to reagents such as Polybrene. It is ideal for transduction of nonpermissive cells such as primary cells and stem cells. 40 transductions.
CPC Scientific Ac-Tyr-Val-Lys-Asp-CHO 1MG
Affinity ligand for interleukin-1b converting enzyme. Slow binding caspase-1 (ICE) inhibitor with low selectivity.SEQUENCE: Ac-Tyr-Val-Lys-Asp-CHOONE-LETTER SEQUENCE: Ac-YVKD-CHOMOLECULAR FORMULA: C26H39N5O8MOLECULAR WEIGHT: 549.6STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [147821-01-1]SYNONYMS: RESEARCH AREA: ApoptosisREFERENCES:T.L. Graybill et al., Int. J. Peptide Protein Res., 44, 173 (1994)N.A. Thornbery et al., Nature, 356, 768 (1992)SKU(s): CASP-015A
Carnabio Usa Inc MRCKA(CDC42BPA)/10UG/TRUNCATED
MRCK(CDC42BPA), Truncated protein, Wild type, Amino Acid 1-574, NP_003598.2, Expressed in Insect (sf21); 10microg
Cell Biolabs Inc ViraDuctin™ AAV Transduction Kit, 10 transductions
AAV can infect both dividing and non-dividing cells and can be maintained in the human host cell, creating the potential for genome integration. Because AAV is a naturally defective virus, requiring provision of several factors in trans for productive infection, it is considered the safest viral vector to use. The AAV transduction process includes viral binding and entry, intracellular trafficking, nuclear transport, and viral second strand DNA synthesis. The viral second strand DNA synthesis has been shown to be the rate limiting step, which leads to inefficient transduction by AAV vectors. ViraDuctin™ AAV Transduction Kit is a proprietary formulation designed to increase the transduction efficiency of AAV vectors in a variety of cell types. This kit provides the following advantages: (1) Higher transduction efficiency in many cell types, (2) Easy to use, and (3) It is ideal for transduction of nonpermissive cells such as primary cells and stem cells. 10 transductions/kit.
CPC Scientific Z-Val-Leu-Leu-CHO 1MG
SEQUENCE: Z-Val-Leu-Leu-CHOONE-LETTER SEQUENCE: ZVLL-CHOMOLECULAR FORMULA: C25H39N3O5MOLECULAR WEIGHT: 461.59STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [263563-09-3]SYNONYMS: -Secretase Inhibitor IIRESEARCH AREA: Alzheimer's DiseaseREFERENCES:G. Abbenante, et al., Biochem. Biophys. Res. Commun. 268, 133 (2000)SKU(s): AMYD-113A
Abcam Forskolin, Adenylyl cyclase activator, 5MG
MW 410.5 Da. Cell-permeable activator of adenylyl cyclase. Interacts directly with the catalytic subunit of the enzyme to increase intracellular cAMP levels. Positive inotropic, platelet antiaggregatory and antihypertensive actions in vivo. 3D Growth matrix component used in liver organoid generation.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ZIP, protein kinase Czeta (PKC-zeta) inhibitor
Novel, cell-permeable protein kinase Cζ (PKCζ) inhibitor
The product is subject to the following: Abcam Restricted Use Statement
Thermo Scientific™ Elastase Inhibitor II
A potent irreversible inhibitor of human neutrophil elastase